HA6978 Ganoderma Lucidum Extract Powder

Ganoderma Lucidum Extract Powder Description

Ganoderma Lucidum Extract Powder is a powder that exhibits a deep reddish‐brown colour and an earthy odour. It is derived from a basidiomycete fungus. Its physicochemical profile indicates hygroscopic behaviour. Consequently, storage below 25°C with desiccant packs is required to maintain stability. Accelerated ageing studies have shown less than 3% potency loss over 24 months. The material displays pH‐dependent solubility. It readily disperses in aqueous alkaline solutions (pH >8) and forms colloidal suspensions in acidic media; homogenisation is necessary to obtain uniform dispersion.

Production involves sequential hot water extraction at 85–90°C to preserve polysaccharides. Ethanol precipitation at a 40% concentration is then applied to isolate triterpenoid fractions. This dual‐phase method yields a product standardised to contain no less than 30% triterpenes. These are quantified as ganoderic acids A, F, R, and S by reverse‐phase HPLC-UV detection at 254 nm using USP-grade calibration standards. In addition, β-glucan content is determined to exceed 25% by means of enzymatic hydrolysis with endo-1,3-β-glucanase followed by glucose oxidase quantification.

Quality assurance protocols strictly control residual solvents. GC-MS analysis confirms that ethanol levels remain below 500 ppm. Heavy metal contaminants (arsenic, cadmium, and lead) are maintained within pharmacopeial limits, as verified by ICP-OES. The particle size distribution ranges between 50 µm and 150 µm. A bulk density of approximately 0.35 g/cm³ affects the powder flow during encapsulation. FT-IR spectroscopy confirms structural integrity by showing carbonyl stretches at 1705 cm⁻¹ and broad hydroxyl peaks around 3400 cm⁻¹.

Ganoderma Lucidum Extract Powder Applications

Nutraceuticals: The extract is incorporated into dietary supplements in the form of standardised capsules or powders. It delivers a minimum of 30% triterpenes and over 25% β-glucans. These formulations provide support for cellular redox modulation.

Cosmetics: The extract is formulated in topical serums and anti-ageing creams at an active concentration of 1.5%. Triterpenoid antioxidant properties reduce oxidative stress in epidermal layers. Nanoemulsion delivery systems are utilised to achieve the required dispersion.

Functional Foods: The extract is added to fortified beverages and health bars at weights ranging from 0.2% to 1.0%. Its water-soluble polysaccharide fraction enhances the nutraceutical profile without altering sensory characteristics.

Pharmaceutical Adjuvants: Preclinical models are used to investigate the extract as a bioavailability enhancer for poorly soluble drugs through ganoderic acid-mediated P glycoprotein inhibition. Current research focuses on oncology adjuvant formulations.

Veterinary Health Products: The extract is used in companion animal supplements that target joint mobility through β-glucan-mediated macrophage activation. Standardised granules contain 10% extract within palatable matrices.

Agricultural Biostimulants: The extract is applied in organic farming as a foliar spray at concentrations from 200 to 500 ppm. Its polysaccharide fractions induce systemic acquired resistance in crops against fungal pathogens.

Ganoderma Lucidum Extract Powder Packaging

Our products are packaged in customised cartons of various sizes according to the material dimensions. Small items are securely packed in PP boxes, while larger items are placed in custom wooden crates. Packaging customisation and the use of appropriate cushioning materials are implemented to ensure optimal protection during transport.

Packaging: Carton, Wooden Box, or Customised.

Kindly review the packaging details provided for your reference.

Manufacturing Process

1.       Testing Method

(1)    Chemical Composition Analysis – Techniques such as GDMS or XRF are employed to verify compliance with purity requirements.

(2)    Mechanical Properties Testing – Tests for tensile strength, yield strength and elongation are conducted to assess material performance.

(3)    Dimensional Inspection – The thickness, width and length are measured to ensure adherence to specified tolerances.

(4)    Surface Quality Inspection – Visual and ultrasonic examinations are performed to detect scratches, cracks or inclusions.

(5)    Hardness Testing – Material hardness is determined to confirm uniformity and mechanical reliability.

Please refer to the SAM testing procedures for detailed information.

Ganoderma Lucidum Extract Powder FAQs

Q1. How should I store this extract to maintain potency?

Sealed containers should be stored in cool, dry conditions below 25°C with desiccant packs to prevent moisture absorption. Long-term stability studies confirm a loss of less than 3% active compound over 24 months when stored away from direct light and humidity.

Q2. Can it be incorporated into water-based cosmetic serums?

Yes. Pre-dispersion in alkaline buffers with a pH above 8 improves solubility. For clear serum formulations, polysaccharide-rich fractions obtained through ultrafiltration should be used. This process maintains colloidal stability without surfactants and delivers antioxidant efficacy at concentrations between 1% and 3%.

Q3. Does the earthy odour affect product formulation?

Carbon filtration or encapsulation techniques can reduce the fungal odour without affecting the bioactive content. In functional foods, microencapsulation with modified starches effectively masks undesirable organoleptic properties while preserving β-glucan bioavailability in beverage systems.

Related Information

1.       Common Preparation Methods

Preparation begins with dried fruiting bodies mechanically pulverised into particles measuring between 0.5 mm and 2 mm. Sequential extraction is performed using 60% ethanol at 60°C for 3 hours to solubilise triterpenoids. This is followed by hot water extraction at 95°C for 2 hours to target polysaccharides. The combined extracts are concentrated under vacuum at ≤65°C to preserve thermolabile compounds. The crude concentrate is clarified by ceramic membrane ultrafiltration with a 50 kDa cutoff to remove insoluble chitin and proteins. Further purification is achieved through macroporous resin chromatography (AB-8 type), which selectively adsorbs ganoderic acids and removes pigments. Eluted fractions are spray-dried with a maltodextrin carrier (inlet 140°C, outlet 70°C) to produce a free-flowing powder with a moisture content of ≤5%. Final standardisation adjusts triterpenes to ≥30% (validated by HPLC) and β-glucans to ≥25% (determined by enzymatic assay) through controlled blending of extract lots. Critical process controls include residual solvent monitoring (<50 ppm ethanol) and heavy metal verification (Cd <0.5 ppm, Pb <1 ppm) in accordance with pharmacopeial standards.