HA4841 Dihydromyricetin Powder C15H12O8 (CAS No. 27200-12-0)

Dihydromyricetin Description

Dihydromyricetin (DHM or DMY), sometimes referred to as Ampelopsin or Ampeloptin, is a natural antioxidant flavonoid derived from the Chinese vine tea plants (Ampelopsis grossedentata).

As an active herbal ingredient of the dihydromyricetin extract, it demonstrates significant effectiveness among hangover remedies and has a notable protective effect against alcohol-induced liver damage.

Dihydromyricetin functions as an active free radical scavenger. The percentage inhibition of DPPH can reach 73.3%-91.5% with the IC50 value of 5.4 mmol/L. It significantly reduces the generation of superoxide anion. It also exhibits strong inhibitory action against Staphylococcus aureus, Bacillus subtilis, and Aspergillus flavus, among others. Recent applications have confirmed that dihydromyricetin can reduce anxiety, levels of blood glucose and blood fat; has anti-inflammatory properties; and effectively restrains cell proliferation of certain tumour cells.

Stanford Advanced Materials (SAM) is a wholesale supplier based in the USA, with customers primarily in North America and Europe. The Dihydromyricetin bulk powder originates from natural extract, which is GRAS compliant. SAM provides an effective intoxication blocker and hangover remedy accessible to the general public. We assert that the responsible use of DHM alcohol can substantially diminish the risks associated with alcohol consumption and offer relief for hangover symptoms the following day. Dihydromyricetin reduces anxiety and susceptibility to seizures caused by withdrawal.

Dihydromyricetin Specification

*The above product information is based on theoretical data and is for reference only. Actual specifications may vary.

Dihydromyricetin Applications

1. PREVENT HANGOVERS: Dihydromyricetin (DHM) is referred to as the “antidote to alcohol” due to its effectiveness in preventing intoxication, severe hangovers, and other unpleasant alcohol withdrawal symptoms.
2. PROTECT YOUR LIVER AND BRAIN: Research indicates that dihydromyricetin reduces alcohol-induced damage to the liver and brain.
3. NO MORE WASTED DAYS: Wake up feeling refreshed and alert following a night out. Enjoy yourself at night and maintain productivity the next day.
4. REDUCE ANXIETY, BLOOD GLUCOSE, AND BLOOD FAT: Recent applications have confirmed that dihydromyricetin can reduce anxiety, as well as levels of blood sugar and blood fat; has anti-inflammatory effects; and effectively restrains cell proliferation of specific tumour cells.

Dihydromyricetin Packing

1 kg/ aluminium foil bag, 10 kg/carton, 25 kg/drum or as required.

Our Dihydromyricetin Powder is clearly labelled to ensure efficient identification and quality control. Measures are taken to prevent damage during storage or transportation.

FAQs

Q1: We are developing a hangover relief supplement. What is the primary mechanism by which your Dihydromyricetin powder supports alcohol metabolism and detoxification?

A1: DHM's efficacy relates to its dual-action mechanism on key liver enzymes. It acts as a potent and selective inhibitor of alcohol dehydrogenase (ADH), which slows the initial conversion of alcohol into more toxic acetaldehyde. Furthermore, DHM significantly accelerates the activity of acetaldehyde dehydrogenase (ALDH2), the enzyme responsible for converting acetaldehyde into harmless acetate. This dual action aids in the rapid elimination of acetaldehyde from the system, thereby supporting liver function and mitigating negative effects associated with alcohol consumption.

Q2: For our new line of liver health supplements, we are concerned about the stability of active ingredients. What are the key storage and formulation considerations for DHM powder to maintain its potency and prevent degradation in our final product?

A2: Dihydromyricetin is sensitive to heat, light, and oxygen, which can lead to oxidation and a loss of potency over time. To ensure stability:

Storage: The raw powder should be stored in a cool, dark, and dry place, ideally in a sealed container with desiccant.

Formulation: For your final product, it is advisable to use opaque packaging (e.g., dark glass jars or blister packs) to protect it from light exposure. Incorporating the powder into solid dosage forms such as capsules is preferable. If developing a liquid formulation, incorporating antioxidants (e.g., Vitamin C) can help protect DHM from oxidative degradation and extend its shelf life.

Q3: We are interested in using DHM for its antioxidant and metabolic benefits. Is there any known interaction with common pharmaceutical drugs, and what is the general safety profile we should communicate to our customers?

A3: While DHM is generally recognised as safe (GRAS) for consumption at recommended dosages, its strong effects on liver enzyme systems necessitate caution. Given its modulation of key detoxification enzymes (specifically CYP2E1 and ALDH2), there is a theoretical possibility for it to alter the metabolism and plasma concentration of certain prescription drugs processed by the same pathways. This includes some sedatives, anaesthetics, and other medications. It is advisable to recommend to customers that they consult with a healthcare professional prior to use, especially if they have underlying health conditions or are taking ongoing medication. This ingredient should be positioned as a dietary supplement for wellness support, not as a medical treatment.