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BP10972 OH-PLLA-COOH, Low Molecular Weight Grades, IV ≤ 1 dl/g, Mw ≤ 90 kDa

Catalogue Number BP10972
Composition OH-PLLA-COOH
Form Powder

OH-PLLA-COOH is a low molecular weight grade from our hydroxyl- and carboxyl-terminated poly(L-lactic acid) series. With an intrinsic viscosity ≤ 1 dl/g and a molecular weight ≤ 90 kDa, this product features both hydroxyl and carboxyl functional groups at its chain ends. Stanford Advanced Materials employs tightly controlled polymerisation processes and rigorous GPC/DSC analysis to ensure consistent molecular weight distribution, degradation properties, and end-group functionality across all batches.

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FAQ

What are the key material performance characteristics of this low molecular weight, dual-end-capped PLLA?

Its low molecular weight (≤ 90 kDa) results in shorter polymer chains with reduced entanglement, leading to faster degradation, better solubility, and lower melt or solution viscosity. The dual hydroxyl and carboxyl end-group structure provides enhanced reactivity for further chemical modifications.

What is the practical significance of offering multiple molecular weight sub-grades (e.g., ≤15 kDa, 15–30 kDa, etc.)?

Different sub-grades correspond to varying chain lengths and intrinsic viscosities, allowing users to select materials based on specific application requirements. Lower molecular weight grades dissolve more rapidly and degrade more quickly, making them suitable for short-term functional materials, while slightly higher grades offer improved mechanical controllability whilst maintaining processability.

What role does the dual hydroxyl and carboxyl end-group structure play in low molecular weight systems?

This structure provides two distinct types of reactive chain ends, greatly facilitating further chemical modification, coupling, or use as polymerisation initiators. Even in low molecular weight systems, this dual functionality makes it an ideal "building block" for constructing more complex polymer architectures such as block copolymers, star polymers, or cross-linked networks.

Is this product suitable for biomedical applications? What are its advantages?

Yes, its biocompatibility and controllable degradation make it suitable for certain biomedical applications. For example, it can serve as a component in tissue engineering scaffolds, where its surface carboxyl and hydroxyl groups promote cell adhesion, or as a carrier in drug delivery systems, enabling targeted or responsive release through end-group modification. Its relatively fast degradation rate is suitable for short-term implants or applications requiring timely resorption.

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