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BP10974 OH-PLLA-COOH, High Molecular Weight Grades, IV ≥ 3 dl/g, Mw ≥ 480 kDa

Catalogue Number BP10974
Composition OH-PLLA-COOH
Form Powder

OH-PLLA-COOH represents the high-performance grade within our hydroxyl- and carboxyl-terminated poly(L-lactic acid) series. With an intrinsic viscosity ≥ 3 dl/g and a molecular weight starting from 480 kDa, this product combines end-group functionality with the exceptional mechanical integrity required for demanding applications. Stanford Advanced Materials leverages proprietary high-viscosity polymerisation control and advanced purification techniques to ensure consistent ultra-high molecular weight distribution, precise end-group retention, and reliable batch-to-batch performance for critical medical and industrial uses.

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FAQ

What are the main advantages of high molecular weight OH-PLLA-COOH compared to low and medium molecular weight grades?

The high molecular weight (≥ 480 kDa) provides exceptional mechanical properties, including higher tensile strength, modulus, toughness, and a longer degradation cycle. Its intrinsic viscosity ≥ 3 dl/g indicates high melt strength during processing, making it suitable for forming techniques such as extrusion and injection moulding that require excellent melt stability.

What is the practical value of offering multiple molecular weight sub-grades ranging from 480 kDa to over 2000 kDa?

This fine grading allows users to precisely select materials based on stringent requirements for mechanical performance, processing difficulty, and degradation time of the final product. For instance, ultra-high molecular weight grades (e.g., >1700 kDa) may be used to manufacture implantable devices necessitating long-term structural stability, whilst relatively lower grades such as 480-730 kDa provide a balance between excellent performance and comparatively easier processability.

Is the dual end-group structure still important in high molecular weight systems?

Yes, very important. Although the high molecular weight itself provides excellent bulk properties, the terminal hydroxyl and carboxyl groups provide the material with crucial surface activity and reactive sites. This is vital for applications requiring adhesion to other materials, surface functionalisation (such as promoting cell adhesion), or achieving controlled crosslinking. It is the key link between the material's macroscopic properties and microscopic interfacial functionality.

Which demanding application areas is this product primarily targeting?

High molecular weight OH-PLLA-COOH is primarily aimed at fields with stringent requirements for mechanical properties and long-term stability, including: absorbable orthopedic fixation devices (e.g., bone plates, screws), long-term implantable drug delivery systems, high-load tissue engineering scaffolds, and durable biodegradable industrial products requiring excellent mechanical performance (e.g., prototypes of certain mechanical components).

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