HA6979 Cassia Seed Extract Powder

Cassia Seed Extract Description

Cassia seed extract, standardised to contain no less than 10% anthraquinones and obtained predominantly from an ethanol‐water extraction at temperatures below 60°C, exhibits defined chemical and biological properties that are essential for its function. Chemically, the extract is characterised by high concentrations of bioactive anthraquinones such as emodin and chrysophanol. Its stability is maintained at temperatures up to 80°C; consequently, degradation occurs above this threshold, thereby reducing efficacy. Physically, it appears as a fine, yellowish-brown powder with moderate solubility in water and ethanol, thereby allowing incorporation into formulations without precipitation. Biologically, the extract effectively inhibits α-glucosidase enzymes, a mechanism associated with the regulation of carbohydrate metabolism, and displays distinct bile acid binding properties that modulate lipid pathways without causing cytotoxic effects. These features are verified through rigorous quality controls, including heavy metal limits (lead < 1 ppm) and strict microbiological standards. Its hygroscopic nature necessitates storage in dry, cool conditions to prevent moisture absorption, while its stability in neutral to slightly acidic pH conditions extends shelf life. Overall, the extract has a consistent composition and stability, making it a valuable material for research and development, with all parameters confirmed using standardised analytical methods.

Cassia Seed Extract Applications

• Nutraceuticals: Used in capsule/tablet formulations for metabolic health at 200–500mg per unit dose. The extract utilises α-glucosidase inhibition for carbohydrate management and bile acid binding for lipid regulation.
• Functional Foods: Incorporated into meal replacement shakes and nutrition bars (0.5–2% w/w) to deliver bioactive anthraquinones, while maintaining thermal stability below 80°C.
• Beverages: Employed in powdered drink mixes and functional teas (0.1–0.5% w/v) with solubility providing a clear suspension, requiring pH control between 4.5 and 6.5.
• Cosmeceuticals: Formulated in anti-ageing serums (1–3% concentration), utilising the antioxidant properties of emodin derivatives for UV protection and support of collagen synthesis.
• Animal Feed Additives: Applied in poultry and swine supplements (100–300mg/kg feed) for the modulation of gut health via microbial bile acid metabolism.

Cassia Seed Extract Packaging

Our products are packaged in customised cartons of various sizes according to the material dimensions. Small items are securely packed in PP boxes, while larger items are placed in custom wooden crates. We adhere to packaging customisation protocols and use appropriate cushioning materials to provide protection during transportation.

Packaging: Carton, Wooden Box, or Customised.

Kindly review the packaging details provided for your reference.

Manufacturing Process

1.       Testing Method

(1)    Chemical Composition Analysis – The composition is verified using techniques such as GDMS or XRF to ensure compliance with purity requirements.

(2)    Mechanical Properties Testing – Tensile strength, yield strength, and elongation are measured to assess material performance.

(3)    Dimensional Inspection – Thickness, width, and length are measured to confirm adherence to specified tolerances.

(4)    Surface Quality Inspection – Defects such as scratches, cracks, or inclusions are identified through visual and ultrasonic examination.

(5)    Hardness Testing – Hardness is determined to confirm uniformity and mechanical reliability.

Please refer to the SAM testing procedures for detailed information.

Cassia Seed Extract FAQs

Q1. How should I store cassia seed extract to maintain its effectiveness?

The extract should be stored in airtight, light-resistant containers at room temperature (15–25°C) with relative humidity below 50%. Temperatures above 30°C should be avoided, given that thermal degradation commences at 80°C. This is particularly important for anthraquinones such as emodin, which are affected by heat and moisture.

Q2. Can this extract be combined with other botanicals for enhanced benefits?

Yes, it may be combined with berberine to support glucose metabolism via α-glucosidase inhibition and with plant sterols for lipid management through bile acid binding. Compatibility testing is recommended when processing temperatures exceed 60°C.

Q3. Is there a risk of gastrointestinal discomfort with long-term use?

At standard formulation levels (≤500mg/dose), studies indicate no significant adverse effects. Formulations should maintain anthraquinone content below 15% because higher concentrations may influence gut motility. It is essential to adhere to regional regulatory limits for anthraquinone derivatives in final products.

Related Information

Common Preparation Methods

The standardised extraction process begins with dried Cassia obtusifolia seeds milled to 40–60 mesh particles. Defatting is performed prior to the primary extraction using 70% aqueous ethanol at a 1:10 solid-to-solvent ratio under reflux at 60°C for 2 hours. The resulting extract is concentrated under vacuum at temperatures not exceeding 50°C, thereby preserving thermolabile anthraquinones. Subsequent sequential membrane filtration (0.45μm → 0.22μm) is applied to remove macromolecular impurities. The concentrate is then spray-dried with a maltodextrin carrier (20% w/w) at inlet/outlet temperatures of 160°C/65°C, respectively, yielding a free-flowing powder standardised to 40% total anthraquinones. Critical quality control measures include HPLC quantification of emodin, chrysophanol, and physcion, with residual solvent levels maintained below ICH Q3C limits.