HA6997 Hawthorn Leaf Extract Powder

Hawthorn Leaf Extract Powder Description

Hawthorn Leaf Extract Powder is characterized as a fine, hygroscopic powder ranging from light brown to yellowish, with a distinctive bitter taste and herbal odour. Its primary bioactive constituents include flavonoid glycosides, notably vitexin-2''-O-rhamnoside (≥8.8%) and hyperoside (≥0.3%), alongside quercetin, rutin, and triterpenoid saponins. Chemically, these flavonoids exhibit potent free-radical scavenging capacity through hydrogen atom donation, inhibiting lipid peroxidation with IC50 values lower than synthetic antioxidants such as BHT. The extract demonstrates thermolability, degrading above 60°C, and low-heat processing is necessary to preserve efficacy. It shows pH-dependent solubility, readily dissolving in hydroalcoholic solutions but forming colloids in water due to polyphenol aggregation. Stability requires protection from UV light, moisture, and oxygen to prevent oxidation of phenolic rings. Analytical profiles confirm heavy metal residues within pharmacopeial limits (lead ≤20 ppm) and microbial contaminants controlled to ≤1,000 CFU/g. Standardized extracts maintain ≥80% total flavonoids (as rutin equivalents), validated by HPLC and UV spectrophotometry. The hygroscopic nature necessitates airtight storage below 25°C for a shelf life of 24 months.

Hawthorn Leaf Extract Powder Applications

• Pharmaceuticals and Nutraceuticals: Formulated into capsules, tablets, and syrups for cardiovascular support. Its flavonoids enhance coronary blood flow, reduce angina symptoms, and regulate hypertension by inhibiting angiotensin-converting enzyme (ACE). Standardized extracts (≥90% total flavonoids) are clinically applied for hyperlipidemia management, reducing serum LDL cholesterol and triglycerides while elevating HDL levels.
• Functional Foods and Beverages: Incorporated into heart-health tonics, teas, and meal replacements. Acts as a natural antioxidant preservative in oils and meats, reducing peroxide formation by 17.8% and extending shelf life. It interacts with vitamin C in functional drinks to amplify free-radical scavenging and improve endothelial function.
• Cosmetics and Personal Care: Incorporated into anti-aging serums and creams for antioxidant protection. Flavonoids inhibit collagenase and elastase degradation, reducing wrinkles and UV-induced photoaging. Anti-inflammatory effects mitigate redness in sensitive or rosacea-prone skin at concentrations of 0.5%–2%.
• Agriculture and Biopesticides: Applied as a biopesticide against Spodoptera litura larvae. Alkaloids disrupt insect molting and feeding behaviours, providing residue-free crop protection. Also embedded in active packaging films to inhibit meat oxidation by 34%.
• Biomedical Research: Studied neuroprotective mechanisms against ischaemic stroke via NMDA receptor modulation. Emerging applications examine vitexin’s potential in diabetic nephropathy by suppressing renal oxidative stress and fibrosis pathways.

Hawthorn Leaf Extract Powder Packaging

Our products are packaged in customised cartons of various sizes based on the material dimensions. Small items are securely packed in PP boxes, while larger items are placed in custom wooden crates. We ensure strict adherence to packaging customisation and the use of appropriate cushioning materials to provide optimal protection during transportation.

Packaging: Carton, Wooden Box, or Customised.

Kindly review the packaging details provided for your reference.

Manufacturing Process

1.       Testing Method

(1)    Chemical Composition Analysis - Verified using techniques such as GDMS or XRF to ensure compliance with purity requirements.

(2)    Mechanical Properties Testing - Includes tensile strength, yield strength, and elongation tests to assess material performance.

(3)    Dimensional Inspection - Measures thickness, width, and length to ensure adherence to specified tolerances.

(4)    Surface Quality Inspection - Checks for defects such as scratches, cracks, or inclusions through visual and ultrasonic examination.

(5)    Hardness Testing - Determines material hardness to confirm uniformity and mechanical reliability.

Please refer to the SAM testing procedures for detailed information.

Hawthorn Leaf Extract Powder FAQs

Q1. Will this assist my high blood pressure?

Yes. Its flavonoids relax blood vessels and inhibit ACE enzymes. Taking 300 mg twice daily may lead to a systolic pressure drop of 8–10 mmHg within 4–6 weeks. Pairing with magnesium can enhance effects.

Q2. Can I take it with my blood thinner (warfarin)?

Avoid the combination. Flavonoids may potentiate anticoagulant effects, increasing bleeding risk. Consult your doctor before use with any blood-thinning medication.

Q3. Why does it cause mild stomach upset?

Tannins in the raw extract may irritate the gastric mucosa. Choose enteric-coated capsules or take with meals. Start with 100 mg/day to assess tolerance.

Related Information

1.       Common Preparation Methods

The production of Hawthorn Leaf Extract Powder begins with sustainably harvested Crataegus pinnatifida leaves, typically dried at ≤40°C to preserve thermolabile flavonoids. Coarsely ground leaves undergo extraction with 50%–70% ethanol (55–60°C) in a 10:1 solvent-to-material ratio for 2 hours, repeated twice. The combined filtrate is concentrated under vacuum to remove ethanol, diluted with an equal volume of water, and purified via D101 macroporous resin chromatography. Target flavonoids are eluted using gradient ethanol (30%–70%), with fractions concentrated to a relative density of 1.10 (60°C). The resulting clear paste is spray-dried with maltodextrin as a carrier, yielding a fine powder standardized to ≥80% total flavonoids and ≥8.8% vitexin-2''-O-rhamnoside. Quality control includes HPLC validation, residual solvent testing (ethanol ≤5,000 ppm), heavy metal screening, and microbial analysis to ensure compliance with international safety standards.