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  • The Argo: A 65,536 channel recording system for high density neural recording in vivo

    • The Argo: A 65,536 channel recording system for high density neural recording in vivo

    Title The Argo: A 65,536 channel recording system for high density neural recording in vivo
    Authors Kunal Sahasrabuddhe, Aamir A. Khan, Aditya P. Singh, Tyler M. Stern, Yeena Ng, Aleksandar Tadi?, Peter Orel, Chris LaReau, Daniel Pouzzner, Kurtis Nishimura, Kevin M. Boergens, Sashank Shivakumar, Matthew S. Hopper, Bryan Kerr, Mina-Elraheb S. Hanna, Robert J. Edgington, Ingrid McNamara, Devin Fell, Peng Gao, Amir Babaie-Fishani, Sampsa Veijalainen, Alexander V. Klekachev, Alison M. Stuckey, Bert Luyssaert, Takashi D. Y. Kozai, Chong Xie, Vikash Gilja, Bart Dierickx, Yifan Kong, Malgorzata Strak
    Magazine bioRxiv
    Date 07/17/2020
    DOI 10.1101/2020.07.17.209403
    Introduction This paper presents the Argo System, an advanced, massively parallel neural recording system. It integrates platinum-iridium microwire electrode arrays with a CMOS voltage amplifier array. The Argo system represents a significant advancement in in vivo neural recording, achieving the highest channel count to date by enabling simultaneous recording from 65,536 channels at over 32 kHz and 12-bit resolution. Engineered for cortical recordings, it functions effectively with both penetrating and surface microelectrodes. Validation involved capturing spiking activity from 791 neurons in rats and cortical surface Local Field Potential (LFP) activity from over 30,000 channels in sheep. While presently configured for head-fixed recording, the microwire-CMOS design holds substantial promise for clinical application, laying the groundwork for future high data rate intracortical implants.
    Quote Kunal Sahasrabuddhe, Aamir A. Khan and Aditya P. Singh et al. The Argo: A 65,536 channel recording system for high density neural recording in vivo. 2020. DOI: 10.1101/2020.07.17.209403
    Element Platinum (Pt) , Iridium (Ir) , Silicon (Si)
    Industry Medical Devices , Research & Laboratory , Electronics
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