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BP10978 OH-PDLA-OH, Low Molecular Weight Grades, IV ≤ 1 dl/g, Mw ≤ 90 kDa

Catalogue Number BP10978
Composition OH-PDLA-OH
Form Powder

OH-PDLA-OH is a low molecular weight grade from our dihydroxy-terminated poly(D-lactic acid) series. With an intrinsic viscosity ≤ 1 dl/g and a molecular weight ≤ 90 kDa, this product features two hydroxyl groups at both chain ends. The D-configured backbone offers distinct stereocomplexation potential with PLLA, while the symmetrical dihydroxy structure provides enhanced symmetry and reactivity for chain extension, crosslinking, or as a macroinitiator. Stanford Advanced Materials employs controlled synthesis to ensure consistent molecular weight, precise end-group fidelity, and excellent batch-to-batch reproducibility for applications requiring well-defined, reactive building blocks.

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FAQ

What is the key structural difference and advantage of OH-PDLA-OH having two hydroxyl end groups?

The symmetrical dihydroxy termination provides a balanced and highly reactive structure ideal for chain extension reactions (e.g., with diisocyanates to form polyurethanes), serving as a telechelic macroinitiator for ring-opening polymerisation, or creating symmetric block copolymers. This dual functionality doubles the potential modification sites compared to mono-hydroxy polymers, offering greater versatility in polymer architecture design.

How does the D-lactide configuration influence its properties and applications compared to L-lactide based diols?

The D-configured backbone enables this diol to form stereocomplexes with PLLA. This capability is particularly valuable when it is used as a building block; the resulting polymers or networks can inherit enhanced thermal stability and mechanical properties from the stereocomplex structure, opening avenues for high-performance, degradable materials that are more challenging to achieve with low molecular weight L-lactide-based diols alone.

Why is this low molecular weight, dihydroxy-terminated PDLA suitable for electronics and biomedical applications?

Its low viscosity ensures excellent processability into thin films or precise microstructures for flexible electronics. The dual hydroxyl groups allow for covalent bonding to other materials (e.g., substrates, drug molecules), improving adhesion and enabling controlled release. Additionally, its biocompatibility and predictable degradation make it ideal for transient implants, sensor coatings, or as a degradable linker in drug-polymer conjugates.

What is the practical value of offering multiple precise molecular weight sub-grades?

Different sub-grades allow for precise tuning of degradation rates, mechanical properties, and solubility. For example, ultra-low Mw grades (≤15 kDa) are suitable for rapid-degrading temporary carriers or plasticisers, while higher sub-grades (55–90 kDa) provide improved mechanical integrity for structural components in scaffolds or composite matrices, all while maintaining the same high reactivity of the dihydroxy end groups.

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