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BP10979 OH-PDLA-OH, Medium Molecular Weight Grades, IV: 1–3 dl/g, Mw: 90–480 kDa

Catalogue Number BP10979
Composition OH-PDLA-OH
Form Powder

OH-PDLA-OH is a medium molecular weight grade from our dihydroxy-terminated poly(D-lactic acid) series. With an intrinsic viscosity between 1–3 dl/g and a molecular weight range of 90–480 kDa, this product features two hydroxyl groups at both chain ends. The D-configured backbone provides distinct stereocomplexation potential with PLLA, whilst the extended chain length and symmetrical dihydroxy structure offer enhanced mechanical properties and reactivity for demanding chain extension, crosslinking, and network-forming applications. Stanford Advanced Materials employs controlled polymerisation to ensure consistent molecular weight distribution, high end-group fidelity, and excellent batch-to-batch reproducibility for advanced material engineering.

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What are the key advantages of medium molecular weight OH-PDLA-OH over its low molecular weight counterpart?

The medium molecular weight range (90–480 kDa) provides significantly longer polymer chains with increased entanglement. This results in enhanced mechanical strength, higher melt viscosity for better processing control, and extended, more predictable degradation profiles. It retains the dual hydroxyl end-group reactivity and stereocomplexation potential but offers improved structural integrity for applications requiring longer-term performance.

How does the symmetrical dihydroxy termination benefit processing and application in medium molecular weight systems?

In medium molecular weight polymers, the symmetrical dihydroxy structure is ideal for creating highly uniform polymer networks and block copolymers via reactions with difunctional agents (e.g., diisocyanates, diacids). This symmetry promotes consistent crosslink density and polymer architecture, leading to materials with more predictable mechanical and degradation properties, which is crucial for implantable devices and controlled release matrices.

What role does the D-lactide configuration play in the performance of this medium molecular weight diol?

The D-configured backbone enables the diol to act as a key component in forming stereocomplexes when combined with PLLA-based polymers. In medium molecular weight systems, this can impart a significant enhancement to the thermal stability (increased melting point) and mechanical strength of the resulting materials, making them suitable for applications where both high performance and biodegradability are required.

What are the primary application areas for medium molecular weight OH-PDLA-OH?

This grade is ideally suited for medium-to-long-term biomedical implants (e.g., absorbable sutures, fixation devices, tissue engineering scaffolds) requiring a balance of strength and controlled degradation. It is also excellent as a reactive building block for synthesising high-performance, stereocomplex-enhanced biodegradable polymers (e.g., for durable coatings or composites) and serves as a matrix for sustained drug delivery systems over weeks to months.

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