BP10982 OH-PDLA-COOH, Medium Molecular Weight Grades, IV: 1–3 dl/g, Mw: 90–480 kDa

OH-PDLA-COOH, Medium Molecular Weight Grades, IV: 1–3 dl/g, Mw: 90–480 kDa Description

OH-PDLA-COOH (Medium Mw Grade) is an asymmetrically end-functionalized poly(D-lactic acid) with a molecular weight range of 90–480 kDa and intrinsic viscosity between 1–3 dl/g. Its medium chain length provides an optimal balance of mechanical strength, processability, and controllable degradation. The hydroxyl and carboxyl end groups offer complementary reactivity for chemical modification, conjugation, and network formation, while the D-configured backbone enables valuable stereocomplexation. This combination makes it a versatile material for engineering durable, high-performance, and functionally tailored biodegradable systems.

OH-PDLA-COOH, Medium Molecular Weight Grades, IV: 1–3 dl/g, Mw: 90–480 kDa Applications

1.      Polymer Synthesis & Functional Materials
- Heterotelechelic Building Block: Used for synthesising well-defined A-B-A type block copolymers, graft polymers, or cross-linked networks via sequential reactions utilising both end groups.
- Stereocomplex-Enhanced Material Component: Incorporated into polymer blends with PLLA to create materials with improved thermal and mechanical properties through stereocomplexation.

2.      Biomedical Devices & Tissue Engineering
- Structural Polymer for Medium-Term Implants: Employed in the fabrication of absorbable surgical meshes, screws, and other fixation devices that require reliable mechanical support over months.
- Functionalised Scaffold Matrix: Used as a base polymer for tissue engineering scaffolds, where the carboxyl group can be used to immobilise growth factors or cell-adhesive peptides to guide tissue regeneration.

3.      Controlled Release & Advanced Formulations
- Matrix for Sustained Drug Delivery: Serves as a polymeric carrier for controlled release formulations, with degradation kinetics and release profiles adjustable via molecular weight sub-grades and end-group modification.
- Reactive Coating for Medical Devices: Applied as a functional coating on implants or catheters, where the end groups allow for covalent attachment of antimicrobial agents or lubricious layers.

OH-PDLA-COOH, Medium Molecular Weight Grades, IV: 1–3 dl/g, Mw: 90–480 kDa Packing

The product is supplied in vacuum-sealed, moisture-proof packaging with desiccant to ensure stability during transportation and storage. We offer flexible packaging sizes tailored to customer requirements from R&D to production scale.

Additional Information

Medium molecular weight hydroxy-carboxyl heterotelechelic PDLA represents a strategically important class of polymers where chain length and asymmetric functionality are jointly optimised. It provides the necessary mechanical integrity for longer-term applications while retaining the versatile chemical handles needed for advanced material design.

Stanford Advanced Materials (SAM) specialises in the precise synthesis of such structurally defined, end-functionalised polymers. Through controlled polymerisation and rigorous analytics, SAM ensures high fidelity of both end groups, narrow molecular weight distribution, and consistent performance. This enables the development of biodegradable materials for applications ranging from regenerative medicine to functional coatings, where a balance of durability, reactivity, and controlled degradation is essential.