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BP10983 OH-PDLA-COOH, High Molecular Weight Grades, IV ≥ 3 dl/g, Mw ≥ 480 kDa

Catalogue Number BP10983
Composition OH-PDLA-COOH
Form Powder

OH-PDLA-COOH is a high molecular weight grade from our hydroxy-carboxyl heterotelechelic poly(D-lactic acid) series. Designed for applications requiring extended structural integrity and long-term performance, this product features an intrinsic viscosity ≥ 3 dl/g and a molecular weight ≥ 480 kDa. Its asymmetric hydroxyl/carboxyl end groups provide versatile reactivity for advanced polymer architectures and surface functionalisation, while the D-configured backbone enables effective stereocomplexation. Stanford Advanced Materials employs proprietary high-viscosity polymerisation and stringent purification to ensure precise molecular weight control, high end-group fidelity, and reliable performance for the most demanding material challenges.

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FAQ

What types of long-term applications are best suited for high molecular weight OH-PDLA-COOH?

This grade is specifically designed for applications requiring sustained mechanical strength, slow degradation over months to years, and high melt stability. It is ideal for long-term absorbable orthopedic implants (e.g., bone plates, screws), high-load tissue engineering scaffolds, durable biodegradable industrial components, and as a key building block for ultra-strong, covalently cross-linked polymer networks.

How do the asymmetric hydroxyl and carboxyl end groups function in ultra-high molecular weight systems?

Even at very high molecular weights, the heterotelechelic structure remains critically functional. It allows this polymer to serve as a macromolecular cross-linker or chain extender in the synthesis of dense, high-strength networks (e.g., polyurethanes, polyanhydrides). The carboxyl group also provides a site for covalent surface modification or bioconjugation, enabling the creation of long-lasting, functionalised implants or devices with tailored bio-interfaces.

What is the benefit of the D-lactide configuration in such high-performance applications?

The D-configured backbone enables the formation of stereocomplexes when combined with PLLA-based polymers. This interaction is key to developing materials with significantly enhanced thermal stability (melting point > 200°C) and improved mechanical properties, making this grade invaluable for applications where high temperature resistance and exceptional durability are required alongside biodegradability.

Why are multiple sub-grades offered within the high molecular weight range?

The range of sub-grades allows for precise matching of material properties to specific performance and processing requirements. For example, a grade around 480–1,020 kDa may provide an excellent balance for manufacturing complex medical devices, while grades above 1,700 kDa are selected for applications demanding the highest mechanical integrity and longest degradation timeline, such as certain load-bearing structural implants.

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