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BP10985 PLGA 50:50, Lauryl Ester Terminated, IV: 0.18–0.55 dl/g, Mw: 15–70 kDa

Catalogue Number BP10985
CAS Number 26780-50-7
Composition Poly(D, L-lactide-co-glycolide) 50:50, Lauryl Ester Terminated
Form Powder

BP10985 is a medium molecular weight PLGA 50:50 copolymer with standard lauryl ester termination, characterised by an intrinsic viscosity (IV) range of 0.18–0.55 dl/g and a molecular weight (Mw) range of 15–70 kDa. The lauryl ester end group provides enhanced hydrophobicity and predictable degradation profiles. This material is engineered for diverse industrial and functional applications requiring a balance of mechanical strength and processability. Its balanced monomer ratio enables excellent processing versatility and tunable release kinetics. Stanford Advanced Materials (SAM) ensures consistent quality through controlled polymerisation, supporting sustainable and reproducible product development. Products with other specific molecular weight ranges or custom ester end groups are available upon request.

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FAQ

What are the key advantages of lauryl ester termination?

Lauryl ester termination provides increased hydrophobicity compared to standard ester or acid end groups, which can slow initial water uptake, moderate early-stage degradation, and enhance compatibility with hydrophobic actives or matrices.

What is the typical degradation time for this material?

Due to its medium molecular weight range (15–70 kDa), this grade is designed for intermediate-term degradation, typically ranging from a few months to over a year under physiological or ambient environmental conditions. The exact timeframe depends on the specific environment (e.g., temperature, pH, moisture) and the chosen molecular weight sub-grade.

How does the medium viscosity benefit processing?

The moderate intrinsic viscosity (0.18–0.55 dl/g) ensures good solubility in common organic solvents while providing sufficient solution viscosity for applications such as film casting, fibre spinning, or the formation of durable microspheres and implants with controlled morphology.

In which applications is this medium molecular weight grade most suitable?

This grade is suitable for applications requiring a balance of processability and durability, such as functional coatings, sustained-release formulations (e.g., weeks to months), biodegradable composites, and intermediate-term packaging materials.

Can you supply PLGA with different molecular weights or terminal groups?

Yes. We offer a range of PLGA copolymers with varying monomer ratios, molecular weights, and end-group functionalities (including acid-terminated and other ester terminations). Please contact our technical sales team to discuss your specific requirements.

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