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BP10986 PLGA 50:50, Lauryl Ester Terminated, IV ≥ 0.55 dl/g, Mw ≥ 70 kDa

Catalogue Number BP10986
CAS Number 26780-50-7
Composition Poly(D, L-lactide-co-glycolide) 50:50, Lauryl Ester Terminated
Form Powder

BP10986 is a high molecular weight PLGA 50:50 copolymer with standard lauryl ester termination, characterised by an intrinsic viscosity (IV) ≥ 0.55 dl/g and a molecular weight (Mw) ≥ 70 kDa. The lauryl ester end group provides enhanced hydrophobicity and predictable long-term degradation profiles. This material is engineered for demanding industrial and functional applications requiring durable mechanical performance, extended structural integrity, and prolonged release kinetics. Its balanced monomer ratio and high molecular weight enable excellent toughness and processability for advanced manufacturing. Stanford Advanced Materials (SAM) ensures consistent quality through controlled polymerisation, supporting sustainable and reproducible product development. Products with other specific molecular weight ranges or custom ester end groups are available upon request.

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FAQ

What are the key advantages of lauryl ester termination?

Lauryl ester termination provides enhanced hydrophobicity compared to standard ester or acid end groups, which significantly slows initial water uptake, extends the induction period before bulk degradation begins, and improves compatibility with highly hydrophobic actives or polymer matrices.

What is the typical degradation time for this material?

Owing to its high molecular weight (Mw ≥ 70 kDa) and lauryl ester end group, this grade is intended for long-term degradation, typically spanning several months to multiple years under physiological or ambient environmental conditions. The precise timeframe is highly contingent upon the specific application environment (e.g., temperature, pH, enzymatic activity).

How does the high viscosity benefit processing and final product performance?

The high intrinsic viscosity (≥ 0.55 dl/g) provides excellent melt strength and solution rheology, making it suitable for processes such as extrusion, injection moulding, and the production of high-solids-content coatings or solid monoliths. This results in final products with enhanced mechanical properties, dimensional stability, and controlled porosity.

In which applications is this high molecular weight grade most suitable?

This grade is ideal for applications requiring long-term durability and controlled degradation, such as high-strength biodegradable composites, long-lasting functional coatings (e.g., for corrosion protection), engineered mulch films, and sustained-release systems designed for release over many months or years.

Can you supply PLGA with different molecular weights or end groups?

Yes. We offer a full range of PLGA copolymers with varying monomer ratios, molecular weights (ranging from low to very high), and end-group functionalities. Please contact our technical sales team to discuss custom synthesis for your specific application requirements.

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