BP10991 PLGA 50:50, Carboxyl-Terminated, IV: 0.18–0.55 dl/g, Mw: 15–70 kDa

PLGA 50:50, Carboxyl-Terminated, IV: 0.18–0.55 dl/g, Mw: 15–70 kDa Description

BP10991 is a carboxyl-terminated PLGA 50:50 copolymer with a medium to high molecular weight range (15–70 kDa) and corresponding intrinsic viscosity (0.18–0.55 dl/g). The carboxyl end groups enhance hydrophilicity and facilitate more controlled, predictable hydrolytic degradation compared to non-functionalised or ester-capped analogues. This makes it particularly suitable for applications requiring extended release profiles or longer-term structural support in physiological environments.

PLGA 50:50, Carboxyl-Terminated, IV: 0.18–0.55 dl/g, Mw: 15–70 kDa Applications

1.         Biomedical & Drug Delivery
   - Used as a matrix in sustained-release drug delivery systems, where its controlled degradation enables prolonged therapeutic release.
   - Applied in tissue engineering as a structural scaffold with predictable resorption rates to match tissue regeneration timelines.

2.         Implantable Medical Devices
   - Incorporated into bioresorbable implants, sutures, and orthopaedic fixation devices that require gradual degradation over weeks to months.
   - Used as a coating or composite material for implants to modulate host response and integration through controlled polymer erosion.

3.        Pharmaceutical & Biomaterials Research
   - Serves as a reference material for studying the effects of molecular weight and end-group chemistry on degradation kinetics and drug release behaviour.
   - Utilised in the development of advanced formulations such as microspheres, fibres, and porous scaffolds for regenerative medicine.

PLGA 50:50, Carboxyl-Terminated, IV: 0.18–0.55 dl/g, Mw: 15–70 kDa Packing

The product is supplied in vacuum-sealed, moisture-barrier aluminium bags with desiccant to ensure stability during shipping and storage. Available in a range of sizes from small R&D samples to bulk industrial quantities. Custom packaging, labelling, and documentation can be provided to meet specific customer or regulatory requirements.

Additional Information

PLGA copolymers with carboxyl termination offer a versatile platform for biomedical innovation, combining tunable degradation with potential for further chemical functionalisation. The controlled molecular weight and viscosity of BP10991 make it especially suitable for applications requiring consistent performance over extended durations.

Stanford Advanced Materials (SAM) is committed to supporting advanced research and product development with high-quality, well-characterised polymer solutions. Our team is available for technical consultation, custom synthesis inquiries, and collaboration on material integration into your next-generation devices or formulations.

Regulatory Note: This material is intended for research and industrial applications. Users are responsible for ensuring compliance with all relevant safety, quality, and regulatory guidelines applicable to their intended use and market.