BP10995 PLGA 75:25, Lauryl Ester Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa

PLGA 75:25, Lauryl Ester Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa Description

BP10995 is a lauryl ester-terminated PLGA 75:25 copolymer defined by its high molecular weight (Mw ≥ 106 kDa) and corresponding high intrinsic viscosity (IV ≥ 0.75 dl/g). This specification results in a material with a prolonged degradation profile and increased mechanical performance. The 75:25 monomer ratio establishes a foundation for slower hydrolysis, while the extended polymer chain length further delays the loss of structural integrity. The lauryl ester end group provides an additional layer of hydrophobicity for precise degradation kinetics control. This combination makes it an ideal choice for formulators and engineers designing systems where longevity and sustained performance are key parameters.

PLGA 75:25, Lauryl Ester Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa Applications

1.         Long-Term Biomedical Implants & Devices
   - Matrix material for bioresorbable orthopedic implants (e.g., screws, pins, plates) designed to provide mechanical support throughout extended healing processes.
   - Fabrication of implants for sustained drug delivery over periods of several months to a year or more.

2.         Advanced Drug Delivery Systems
   - Core polymer for creating microspheres, rods, or films aimed at ultra-sustained release of active pharmaceutical ingredients (APIs).
   - Component in implantable delivery devices or reservoirs requiring stable, slow-eroding polymer walls.

3.         Durable Biodegradable Materials
   - Used in the development of high-strength, biodegradable composites for specialised industrial or environmental applications where slow breakdown is desired.
   - As a robust binder or coating in applications demanding both functional longevity and ultimate biodegradability.

PLGA 75:25, Lauryl Ester Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa Packing

To ensure stability, the product is packaged under a protective atmosphere in high-barrier, moisture-proof aluminium foil bags with desiccant. These are further secured within rigid outer containers. We offer this specialised packaging in sizes suitable for research through to production-scale volumes.

Additional Information

The high molecular weight variant of PLGA 75:25 addresses application needs distinct from those met by lower Mw grades, focusing on extended temporal performance and enhanced mechanical demands. Its properties are the result of targeted polymerisation control.

Stanford Advanced Materials (SAM) provides dedicated technical support for projects utilising this high Mw PLGA, including assistance with grade selection, formulation challenges, and custom synthesis inquiries.

Regulatory Note: This material is intended for use in industrial and biomedical product development. Its incorporation into medical devices or implants requires thorough biocompatibility and performance testing specific to the intended application, in accordance with all relevant regulatory standards (e.g., ISO 10993, FDA, CE MDR). Compliance is the responsibility of the end-user.