BP10997 PLGA 75:25, Hydroxyl Terminated, IV: 0.18–0.75 dl/g, Mw: 15–106 kDa

PLGA 75:25, Hydroxyl Terminated, IV: 0.18–0.75 dl/g, Mw: 15–106 kDa Description

BP10997 is a hydroxyl-terminated PLGA 75:25 copolymer engineered within a medium-to-high molecular weight spectrum (Mw 15–106 kDa, IV 0.18–0.75 dl/g). This material merges the extended degradation profile and mechanical characteristics of higher Mw PLGA 75:25 with the distinctive hydrophilic and chemically reactive properties imparted by the terminal hydroxyl groups. It enables the fabrication of constructs that maintain integrity over extended periods while offering compatibility with aqueous environments and providing anchor points for biomolecule conjugation or polymer network formation. This combination makes it a tool for developing functional biodegradable materials.

PLGA 75:25, Hydroxyl Terminated, IV: 0.18–0.75 dl/g, Mw: 15–106 kDa Applications

Biomedical Devices
   - Used as a matrix in drug delivery systems to achieve gradual release by leveraging its biodegradable properties. This application minimises burst release while supporting patient safety.
   - Applied in tissue engineering scaffolds to promote cell adhesion and controlled degradation. Its hydrolytic breakdown aligns with tissue regeneration requirements.

Research and Development
   - Serves as a model polymer for studying biodegradation kinetics in bioresorbable devices. The consistent molecular weight range facilitates reproducible experimental conditions.
   - Used in formulation studies to assess polymer-drug interactions, enabling optimisation of delivery profiles through controlled polymer architecture.

PLGA 75:25, Hydroxyl Terminated, IV: 0.18–0.75 dl/g, Mw: 15–106 kDa Packing

The product is securely packaged in moisture-barrier, sealed pouches to prevent contamination and hydrolysis. Each package is contained in rigid, insulated boxes to minimise temperature fluctuations during transit and storage. Customised options such as bulk packaging or smaller units are available. Storage in a cool, dry environment is recommended to preserve polymer integrity and performance.

Additional Information

The hydroxyl termination fundamentally differentiates this PLGA grade, shifting its property profile towards hydrophilicity and chemical reactivity. Combined with the 75:25 monomer ratio, it occupies a distinct niche, offering a balance of sustained degradation and functional handle ideal for water-compatible formulations.

Stanford Advanced Materials (SAM) is committed to providing high-performance, specialised polymer solutions. Our technical team is available to support your material selection and collaborate on custom synthesis projects to meet unique application needs.

Regulatory Note: This material is designed for industrial and consumer applications. It is the customer's responsibility to ensure compliance with all applicable safety and regulatory requirements for their intended use, especially for applications involving prolonged human or environmental exposure.