BP10998 PLGA 75:25, Hydroxyl Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa

PLGA 75:25, Hydroxyl Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa Description

BP10998 represents a high-performance grade of hydroxyl-terminated PLGA 75:25, characterised by its high intrinsic viscosity (IV ≥ 0.75 dl/g) and molecular weight (Mw ≥ 106 kDa). This combination yields a polymer with mechanical strength, melt viscosity, and solution viscosity, suitable for processing into structures. The 75:25 lactide:glycolide ratio provides a balance between degradation duration and mechanical integrity. The terminal hydroxyl groups moderate surface hydrophobicity and serve as sites for chemical modification, enabling the covalent attachment of bioactive agents or the synthesis of block copolymers. This material is engineered for applications where longevity, durability, and chemical functionality are vital.

PLGA 75:25, Hydroxyl Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa Applications

1.         Healthcare
   - Utilised as an implant scaffold in controlled drug delivery systems to achieve sustained therapeutic release by leveraging predictable hydrolysis kinetics.
   - Applied as a matrix in biodegradable sutures to promote gradual tissue integration by utilising its consistent degradation profile.

2.         Biomedical Research
   - Serves as a substrate for in vitro cell culture studies to simulate tissue environments by employing its tunable erosion properties.
   - Frequently used in tissue engineering to support scaffold structure during regeneration by capitalising on its biocompatible composition.

PLGA 75:25, Hydroxyl Terminated, IV ≥ 0.75 dl/g, Mw ≥ 106 kDa Packing

The product is securely packaged in multi-layer, moisture-barrier, vacuum-sealed aluminised pouches to prevent hydrolysis and oxidative degradation. Primary pouches are then placed within rigid, insulated secondary containers with desiccant to reduce exposure to temperature fluctuations and physical shock during transit and storage. Custom packaging options, including bulk drums, controlled atmosphere packaging, or small aliquot sizes, are available upon request. For optimal shelf-life, store in a freezer (-20 °C) or at minimum in a cool, dry environment (≤ 4 °C).

Additional Information

This high molecular weight, hydroxyl-terminated PLGA 75:25 occupies a strategic niche in the biomaterials portfolio. It transcends the role of a biodegradable polymer by offering a durable and chemically versatile platform. The degradation timeline, governed by its high Mw and 75:25 composition, is coupled with the synthetic utility of the hydroxyl end-group. This allows researchers and engineers to design devices that can persist in the body for predefined, lengthy durations and can be tailored to interact with their biological surroundings in precise ways.

Stanford Advanced Materials (SAM) is dedicated to providing high-specification, consistent polymer solutions. Our technical support team is available to assist with grade selection, processing guidance, and discussions around custom synthesis to meet the demands of your innovative projects.

Regulatory Note: This material is designed for industrial and consumer applications. It is the customer's responsibility to ensure compliance with all applicable safety and regulatory requirements for their intended use, especially for applications involving prolonged human or environmental exposure.