BP10999 PLGA 75:25, Carboxyl-Terminated, IV ≤ 0.18 dl/g, Mw ≤ 15 kDa

PLGA 75:25, Carboxyl-Terminated, IV ≤ 0.18 dl/g, Mw ≤ 15 kDa Description

BP10999 is a carboxyl-terminated PLGA 75:25 copolymer with a controlled molecular weight (Mw ≤ 15 kDa) and intrinsic viscosity (IV ≤ 0.18 dl/g). The carboxylic acid end group enhances hydrophilicity and influences degradation behaviour by accelerating hydrolytic cleavage. This results in a predictable erosion profile, making it suitable for applications requiring controlled release or timed resorption. Available as a free-flowing powder, it facilitates easy processing in solvent-based or melt formulations for biomedical and research use.

PLGA 75:25, Carboxyl-Terminated, IV ≤ 0.18 dl/g, Mw ≤ 15 kDa Applications

1.         Biomedical & Drug Delivery
   - Used as a matrix in controlled-release drug delivery systems, leveraging its predictable degradation to modulate release kinetics.
   - Applied as a scaffold material in tissue engineering, supporting cell growth while degrading in sync with tissue regeneration.

2.         Pharmaceutical & Biotech Research
   - Serves as a model polymer for in vitro degradation and erosion studies, aiding in the development of new biodegradable formulations.
   - Utilised as a carrier for bioactive molecules, enabling tunable release profiles through controlled polymer erosion.

3.        Implantable & Resorbable Medical Devices
   - Incorporated into coatings or matrices for temporary implants, where controlled resorption is required to match healing timelines.
   - Used in combination with other biomaterials to create composite structures with tailored degradation properties.

PLGA 75:25, Carboxyl-Terminated, IV ≤ 0.18 dl/g, Mw ≤ 15 kDa Packing

The product is supplied in vacuum-sealed, moisture-proof aluminium bags with desiccant to ensure stability during transport and storage. Packaging is available in various sizes to accommodate R&D samples through to bulk production orders. Custom labelling and secondary packaging options are also available upon request.

Additional Information

Carboxyl-terminated PLGA polymers offer distinct advantages in applications requiring enhanced hydrophilicity and controlled degradation. The terminal carboxylic acid group not only accelerates erosion but also provides a potential site for further chemical modification, such as conjugation with targeting ligands or cross-linking agents.

Stanford Advanced Materials (SAM) is dedicated to providing high-quality, specialty polymers for advanced applications. Our technical support team is available to assist with material selection, customisation, and integration into your product development process.

Regulatory Note: This material is intended for research and industrial use. It is the customer's responsibility to ensure compliance with all applicable safety, regulatory, and quality standards for their specific application and region.