BP11112 PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 0.5–1.0 dl/g, Mw: 20–49 kDa

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 0.5–1.0 dl/g, Mw: 20–49 kDa Description

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated is synthesised via a controlled polymerisation process, resulting in an intrinsic viscosity range of 0.5–1.0 dl/g and a molecular weight range of 20–49 kDa. The carboxyl end groups provide reactive chain ends suitable for further chemical modification or covalent conjugation. Supplied in granule form, the material is optimised for consistent handling and is suitable for melt-processing methods such as injection moulding and extrusion, as well as solution-based processing like solvent casting. This balance of controlled polymer architecture and process-ready morphology supports reliable performance in biomedical device development and advanced biocompatible applications.

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 0.5–1.0 dl/g, Mw: 20–49 kDa Applications

Healthcare and Biomedical Devices
   - Used as a scaffold material in tissue engineering to achieve enhanced cell adhesion by leveraging its biocompatible and reactive end-group properties.
   - Employed in drug delivery systems to attain controlled release profiles by capitalising on its predictable degradation kinetics.

Industrial and Research Applications
   - Used as a functional component in biodegradable coatings, where its granule form enables consistent feeding and melting, and its modifiable chain ends support chemical anchoring to substrates or other functional layers.
   - Incorporated as a reactive additive in polymer blends to tailor mechanical and degradation behaviours in experimental formulations, leveraging its controlled molecular weight and terminal carboxyl functionality for enhanced compatibility and structure control.

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 0.5–1.0 dl/g, Mw: 20–49 kDa Packing

The material is delivered in sealed, moisture-resistant bags to protect against contamination and environmental exposure. Each package is cushioned with anti-static material to prevent mechanical damage during transport and storage. It should be stored in a dry, temperature-controlled environment. Custom packaging options are available upon request to accommodate specific processing or handling requirements.

Additional Information

HO-PTMC-COOH is a heterotelechelic derivative of poly(trimethylene carbonate) (PTMC), a biodegradable and biocompatible polymer widely studied in the field of biomedical materials. Known for its amorphous nature, it exhibits excellent biocompatibility and biodegradability, and remains in a rubbery state with inherent elasticity at body temperature. Its adjustable degradation profile and processability make it well-suited for applications such as soft tissue engineering, flexible implants, and controlled drug delivery systems. Understanding the relationship between its molecular weight and intrinsic viscosity is essential for tailoring its performance in specific biomedical and industrial contexts.

Unlike conventional PTMC diols, the unique heterobifunctional structure of HO-PTMC-COOH—featuring both hydroxyl (-OH) and carboxyl (-COOH) terminal groups—provides two distinct and orthogonally reactive sites. This enables sequential, directional chemical modifications, such as selective chain extension from the hydroxyl end, followed by targeted conjugation of bioactive molecules, ligands, or other polymers via the carboxyl group. This controlled functionality significantly enhances its versatility in synthesising precisely defined architectures, including asymmetric block copolymers, surface-functionalised materials, and tunable cross-linked networks for advanced biomaterial design.

The dual reactivity of HO-PTMC-COOH expands its utility in advanced manufacturing, formulation processes, and the development of highly customised polymeric systems, particularly where spatial control over chemical functionality is required. Ongoing research continues to refine processing and conjugation techniques to enhance its performance, reliability, and reproducibility across a growing range of applications, from drug-polymer conjugates to modular tissue engineering scaffolds.

Regulatory Note: This material is intended for industrial and research applications. It is the customer's responsibility to ensure compliance with all relevant safety and regulatory standards in their intended use.