BP11115 PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 3.0–4.0 dl/g, Mw: 198–285 kDa

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 3.0–4.0 dl/g, Mw: 198–285 kDa Description

This product is a carboxyl-terminated poly(trimethylene carbonate) (PTMC-COOH) formulation, characterised by an intrinsic viscosity range of 3.0–4.0 dl/g and a molecular weight between 198 and 285 kDa. The defined polymer structure, provided in granule form, ensures controlled handling and processing stability, supporting predictable degradation kinetics in applications requiring consistent material behaviour and post-synthesis functionalisation. The reactive carboxyl terminal groups facilitate targeted chemical modifications, enabling precise integration into advanced biocompatible systems such as controlled-release carriers and structured biomaterials.

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 3.0–4.0 dl/g, Mw: 198–285 kDa Applications

Biomedical Devices
   - Used as a matrix component in drug delivery systems to achieve controlled release by leveraging its predictable degradation rate.
   - Applied as a scaffold in tissue engineering to achieve temporary structural support by leveraging its biocompatible and modifiable surface.

Industrial Composite Fabrication
   - Used as a binding agent in sensor composites to achieve enhanced adhesion by leveraging its controlled molecular weight distribution, ensuring uniform performance.

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 3.0–4.0 dl/g, Mw: 198–285 kDa Packing

The product is sealed in moisture barrier laminated pouches and housed within rigid, cushioned boxes to prevent contamination and physical damage. It is recommended to store the product in a dry, temperature-controlled environment to maintain material stability. Anti-static measures are integrated during packaging, and customisation options are available for batch size and labelling requirements.

Additional Information

HO-PTMC-COOH is a heterotelechelic derivative of poly(trimethylene carbonate) (PTMC), a biodegradable and biocompatible polymer widely studied in the field of biomedical materials. Known for its amorphous nature, it exhibits excellent biocompatibility and biodegradability, and remains in a rubbery state with inherent elasticity at body temperature. Its adjustable degradation profile and processability make it well-suited for applications such as soft tissue engineering, flexible implants, and controlled drug delivery systems. Understanding the relationship between its molecular weight and intrinsic viscosity is essential for tailoring its performance in specific biomedical and industrial contexts.

Unlike conventional PTMC diols, the unique heterobifunctional structure of HO-PTMC-COOH—featuring both hydroxyl (-OH) and carboxyl (-COOH) terminal groups—provides two distinct and orthogonally reactive sites. This enables sequential, directional chemical modifications, such as selective chain extension from the hydroxyl end, followed by targeted conjugation of bioactive molecules, ligands, or other polymers via the carboxyl group. This controlled functionality significantly enhances its versatility in synthesising precisely defined architectures, including asymmetric block copolymers, surface-functionalised materials, and tunable cross-linked networks for advanced biomaterial design.

The dual reactivity of HO-PTMC-COOH expands its utility in advanced manufacturing, formulation processes, and the development of highly customised polymeric systems, particularly where spatial control over chemical functionality is required. Ongoing research continues to refine processing and conjugation techniques to enhance its performance, reliability, and reproducibility across a growing range of applications, from drug-polymer conjugates to modular tissue engineering scaffolds.

Regulatory Note: This material is intended for industrial and research applications. It is the customer's responsibility to ensure compliance with all relevant safety and regulatory standards in their intended use.