BP11116 PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 4.0–5.0 dl/g, Mw: 285–378 kDa

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 4.0–5.0 dl/g, Mw: 285–378 kDa Description

This carboxyl-terminated aliphatic polycarbonate features an intrinsic viscosity range of 4.0–5.0 dl/g and a controlled molecular weight between 285 and 378 kDa. Produced in granule form, the polymer offers enhanced handling consistency and processing stability while maintaining predictable end-group functionality and molecular weight distribution. This material uniformity supports reliable chemical modification and structural control, making it well-suited for applications in biocompatible systems and advanced materials research where reproducible reactivity and performance are essential.

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 4.0–5.0 dl/g, Mw: 285–378 kDa Applications

1.         Biomedical Engineering
   - Used as a scaffold component in tissue engineering to achieve a controlled degradation profile by leveraging its bioresorbability.
   - Applied as a matrix in drug delivery systems to regulate release rates by utilising its predictable end-group functionality.

2.         Advanced Materials
   - Used as an additive in composite formulations to adjust mechanical properties by leveraging its consistent molecular weight distribution.
   - Applied as a coating in biodegradable packaging to enhance environmental performance by utilising its inherent biocompatibility.

PTMC, Poly(trimethylene carbonate), Carboxyl-Terminated, IV: 4.0–5.0 dl/g, Mw: 285–378 kDa Packing

The polymer is packaged in moisture-resistant, anti-static materials and sealed within aluminium bags to mitigate air and moisture exposure. Storage should be in a cool, dry, temperature-controlled environment away from direct sunlight. Anti-contamination measures and secondary containment are integrated into the packaging process, with customised options available to suit specific transport and storage requirements.

Additional Information

HO-PTMC-COOH is a heterotelechelic derivative of poly(trimethylene carbonate) (PTMC), a biodegradable and biocompatible polymer widely studied in the field of biomedical materials. Known for its amorphous nature, it exhibits excellent biocompatibility and biodegradability, and remains in a rubbery state with inherent elasticity at body temperature. Its adjustable degradation profile and processability make it well-suited for applications such as soft tissue engineering, flexible implants, and controlled drug delivery systems. Understanding the relationship between its molecular weight and intrinsic viscosity is essential for tailoring its performance in specific biomedical and industrial contexts.

Unlike conventional PTMC diols, the unique heterobifunctional structure of HO-PTMC-COOH—featuring both hydroxyl (-OH) and carboxyl (-COOH) terminal groups—provides two distinct and orthogonally reactive sites. This enables sequential, directional chemical modifications, such as selective chain extension from the hydroxyl end, followed by targeted conjugation of bioactive molecules, ligands, or other polymers via the carboxyl group. This controlled functionality significantly enhances its versatility in synthesising precisely defined architectures, including asymmetric block copolymers, surface-functionalised materials, and tunable cross-linked networks for advanced biomaterial design.

The dual reactivity of HO-PTMC-COOH expands its utility in advanced manufacturing, formulation processes, and the development of highly customised polymeric systems, particularly where spatial control over chemical functionality is required. Ongoing research continues to refine processing and conjugation techniques to enhance its performance, reliability, and reproducibility across a growing range of applications, from drug-polymer conjugates to modular tissue engineering scaffolds.

Regulatory Note: This material is intended for industrial and research applications. It is the customer's responsibility to ensure compliance with all relevant safety and regulatory standards in their intended use.