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BP11122 PLGA 65:35, Lauryl Ester Terminated, IV: 0.25–0.35 dl/g, Mw: 24–38 kDa

Catalogue Number BP11122
Composition Poly(D, L-lactide-co-glycolide) 65:35, Lauryl Ester Terminated
Form Powder

PLGA 65:35, Lauryl Ester Terminated is a functionalised biodegradable copolymer with a lactide-to-glycolide molar ratio of 65:35. The incorporation of lauryl ester end groups enhances the polymer's hydrophobicity and efficiently modulates its degradation kinetics, making it particularly suitable for sustained-release formulations and hydrophobic drug delivery systems.

Stanford Advanced Materials (SAM) employs controlled synthesis processes and rigorous quality assurance systems, supported by spectroscopic and chromatographic characterisation methods. Intrinsic viscosity is determined using Ubbelohde capillary viscometry, providing key insights into polymer chain length and solution behaviour. Each batch undergoes validated analytical testing to ensure structural consistency, functional reliability, and compliance with specifications for advanced biomedical research and product development.

In addition to the standard 65:35 grade, SAM offers customised synthesis of PLGA copolymers with various lactide-to-glycolide ratios, such as 90:10, 85:15, 80:20, 70:30, 65:35, and 60:40. We also provide tailored molecular weights, end-group modifications, and physical forms to meet diverse application requirements.

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FAQ

How does the intrinsic viscosity range affect the performance of this PLGA product?

The specified intrinsic viscosity of 0.25–0.35 dl/g influences the polymer chain length, which in turn impacts degradation rates and mechanical strength. Adjusting this parameter helps tailor the material for specific time-sensitive biomedical applications.

What effect does the molecular weight range have on biodegradability?

A defined molecular weight range between 24 and 38 kDa controls the degradation process. Lower molecular weights typically degrade faster, while higher ones provide a longer functional lifespan, which is crucial for applications requiring controlled release profiles.

Why is lauryl ester termination significant for this copolymer?

Lauryl ester termination alters the hydrophobicity of the polymer, improving miscibility with other formulations and modulating the degradation behaviour. This functionalisation aids in achieving specific processing characteristics in biomedical devices.

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