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BP11123 PLGA 65:35, Lauryl Ester Terminated, IV: 0.35–0.45 dl/g, Mw: 38–53 kDa

Catalogue Number BP11123
Composition Poly(D, L-lactide-co-glycolide) 65:35, Lauryl Ester Terminated
Form Powder

PLGA 65:35, Lauryl Ester Terminated is a functionalised biodegradable copolymer with a lactide-to-glycolide molar ratio of 65:35. The incorporation of lauryl ester end groups enhances the polymer's hydrophobicity and effectively modulates its degradation kinetics, making it particularly suitable for sustained-release formulations and hydrophobic drug delivery systems.

Stanford Advanced Materials (SAM) employs controlled synthesis processes and rigorous quality assurance systems, supported by spectroscopic and chromatographic characterisation methods. Intrinsic viscosity is determined using Ubbelohde capillary viscometry, providing key insights into polymer chain length and solution behaviour. Each batch undergoes validated analytical testing to ensure structural consistency, functional reliability, and compliance with specifications for advanced biomedical research and product development.

In addition to the standard 65:35 grade, SAM offers customised synthesis of PLGA copolymers with various lactide-to-glycolide ratios, such as 90:10, 85:15, 80:20, 70:30, 65:35, and 60:40. We also provide tailored molecular weights, end-group modifications, and physical forms to meet diverse application requirements.

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FAQ

How does the intrinsic viscosity range influence the polymer’s degradation profile?

The specified intrinsic viscosity (0.35–0.45 dl/g) assists in predicting the polymer degradation rate and mechanical strength. This parameter is critical for ensuring that the material degrades at a controlled rate, which is beneficial for time-dependent biomedical applications.

What effect does the molecular weight range have on processing and end-use performance?

The molecular weight range (38–53 kDa) affects both the polymer’s melt viscosity during processing and its mechanical properties in end-use applications. A defined molecular weight enhances reproducibility in formulation and provides clarity in application-specific performance.

In what ways can lauryl ester termination modify the polymer characteristics?

The lauryl ester termination influences the hydrophobicity and chain-end reactivity, which may affect drug release kinetics and surface interactions in biomedical devices. This modification can be leveraged to tune performance in various biocompatible applications. For further details, contact us.

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