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BP11125 PLGA 65:35, Lauryl Ester Terminated, IV: 0.55–0.65 dl/g, Mw: 70–88 kDa

Catalogue Number BP11125
Composition Poly(D, L-lactide-co-glycolide) 65:35, Lauryl Ester Terminated
Form Powder

PLGA 65:35, Lauryl Ester Terminated is a functionalised biodegradable copolymer with a lactide-to-glycolide molar ratio of 65:35. The incorporation of lauryl ester end groups increases the polymer's hydrophobicity and effectively modulates its degradation kinetics, making it particularly suitable for sustained-release formulations and hydrophobic drug delivery systems.

Stanford Advanced Materials (SAM) employs controlled synthesis processes and rigorous quality assurance systems, supported by spectroscopic and chromatographic characterisation methods. Intrinsic viscosity is determined using Ubbelohde capillary viscometry, providing key insights into polymer chain length and solution behaviour. Each batch undergoes validated analytical testing to ensure structural consistency, functional reliability, and compliance with specifications for advanced biomedical research and product development.

In addition to the standard 65:35 grade, SAM offers customised synthesis of PLGA copolymers with various lactide-to-glycolide ratios, such as 90:10, 85:15, 80:20, 70:30, 65:35, and 60:40. We also provide tailored molecular weights, end-group modifications, and physical forms to meet diverse application requirements.

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FAQ

How does the intrinsic viscosity range affect degradation behaviour in biomedical applications?

The intrinsic viscosity range of 0.55–0.65 dl/g correlates with polymer chain length, which in turn influences the degradation rate. A controlled range ensures predictable hydrolysis, making it suitable for applications such as drug delivery, where consistent material performance is necessary. Contact us for more technical details.

In what ways does molecular weight variation impact drug release profiles?

The molecular weight range of 70–88 kDa influences the polymer’s mechanical strength and degradation kinetics. A higher molecular weight typically results in slower degradation, which can extend the drug release period, while a lower molecular weight may provide a faster release. Contact us for application-specific insights.

What storage conditions are recommended for maintaining polymer integrity?

It is advisable to store the powder in a cool, dry environment away from moisture and direct light. Such conditions minimise premature hydrolysis and preserve the material’s defined viscosity and molecular weight. Contact us for specific storage protocol details.

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