BP11128 PLGA 65:35, Lauryl Ester Terminated, IV: 1.0–2.0 dl/g, Mw: 158–410 kDa

PLGA 65:35, Lauryl Ester Terminated, IV: 1.0–2.0 dl/g, Mw: 158–410 kDa Description

The material is a poly(lactide-co-glycolide) copolymer with a 65:35 ratio that has been modified with a lauryl ester termination. Its intrinsic viscosity (1.0–2.0 dl/g) and molecular weight range (158–410 kDa) determine its degradation rate and mechanical properties. These features are critical when used as a matrix in drug delivery and tissue engineering, ensuring controllable breakdown and biocompatibility during in vivo applications.

PLGA 65:35, Lauryl Ester Terminated, IV: 1.0–2.0 dl/g, Mw: 158–410 kDa Applications

1.         Healthcare
   - Used as a matrix in implantable drug delivery systems to achieve predictable therapeutic release by leveraging its controlled degradation rate.
   - Applied in tissue engineering scaffolds to support cell proliferation by providing a biodegradable framework with adjustable mechanical properties.

2.         Industrial
   - Employed in microencapsulation processes for encapsulating active ingredients to attain uniform particle formation by utilising its precise molecular weight distribution.
   - Integrated in coating formulations to act as a binder that degrades uniformly, enhancing process consistency in commercial manufacturing.

3.         Research and Development
   - Utilised as a base material in laboratory studies to achieve reproducible degradation profiles by taking advantage of its lauryl ester termination.
   - Applied in formulation development to examine drug release kinetics, ensuring reliable experimental outcomes in biocompatibility assessments.

PLGA 65:35, Lauryl Ester Terminated, IV: 1.0–2.0 dl/g, Mw: 158–410 kDa Packing

The product is packaged in sealed, inert containers designed to prevent moisture ingress and contamination. Each container is cushioned with anti-static materials and secured to minimise mechanical disturbances during transit. Storage is recommended at controlled room temperature away from direct sunlight. Custom packaging options, including tamper-evident seals and secondary containment, are available to meet specific handling and storage requirements.

Additional Information

Poly(lactide-co-glycolide) copolymers are widely studied for their biodegradable and tunable properties, which make them suitable for various biomedical applications. The degradation profile can be modulated by adjusting the lactic to glycolic acid ratio and end-group modifications, providing researchers with a versatile material for designing systems that require temporal control over material breakdown. Such innovations have significant implications in developing advanced drug delivery systems and resorbable implants.

Research continues on refining synthesis and quality control measures to ensure that these engineered polymers consistently meet application-specific demands. This ongoing work enhances the understanding of polymer degradation kinetics and influences developments in medical device design and tissue engineering strategies.

Regulatory Note: This material is intended for industrial and research applications. It is the customer's responsibility to ensure compliance with all relevant safety and regulatory standards in their intended use.