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BP11131 PLGA 65:35, Carboxyl-Terminated, IV: 0.18–0.25 dl/g, Mw: 15–24 kDa

Catalogue Number BP11131
Composition Poly(D, L-lactide-co-glycolide) 65:35, Carboxyl-Terminated
Form Powder

PLGA 65:35, Carboxyl-Terminated, IV: 0.18–0.25 dl/g, Mw: 15–24 kDa is a biodegradable copolymer used in controlled release systems and tissue engineering research. Stanford Advanced Materials (SAM) applies quantitative gel permeation chromatography and viscosity analysis for quality assurance. SAM conducts rigorous in-house testing to verify polymer consistency and molecular attributes essential for predictable degradation profiles and performance reliability.

In addition to the standard 65:35 grade, SAM offers customised synthesis of PLGA copolymers with various lactide-to-glycolide ratios, such as 90:10, 85:15, 80:20, 70:30, 65:35, and 60:40. We also provide tailored molecular weights, end-group modifications, and physical forms to meet diverse application requirements.

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FAQ

How does the intrinsic viscosity range affect the degradation rate of this PLGA polymer?

The IV range of 0.18–0.25 dl/g indicates a moderate molecular weight distribution, which governs the polymer’s degradation rate. This balance facilitates predictable hydrolysis and mechanical stability during controlled release applications.

What is the impact of carboxyl termination on polymer interaction with biomolecules?

Carboxyl termination increases the polymer’s hydrophilicity, promoting enhanced interactions with aqueous environments and biomolecules. This modification can improve cell adhesion and degradation kinetics, which are important in tissue engineering and drug delivery systems.

Can this PLGA material be integrated into drug release formulations without additional modifications?

Yes, the specified PLGA formulation is designed for direct incorporation into drug release matrices. Its controlled molecular weight and carboxyl end groups support consistent degradation, providing sustained release over predetermined time frames. For formulation customisation, contact us.

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