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BP11134 PLGA 65:35, Carboxyl-Terminated, IV: 0.45–0.55 dl/g, Mw: 53–70 kDa

Catalogue Number BP11134
Composition Poly(D, L-lactide-co-glycolide) 65:35, Carboxyl-Terminated
Form Powder

PLGA 65:35, Carboxyl-Terminated, IV: 0.45–0.55 dl/g, Mw: 53–70 kDa is a biocompatible polymer with a 65:35 lactic to glycolic acid ratio and carboxyl end-groups that facilitate controlled degradation. Stanford Advanced Materials (SAM) utilises systematic GPC and titrimetric analyses to verify molecular weight and functional termination. Their quality control procedures ensure consistency in formulation, thereby supporting reproducible performance in biomedical research and development.

In addition to the standard 65:35 grade, SAM offers customised synthesis of PLGA copolymers with various lactide-to-glycolide ratios, such as 90:10, 85:15, 80:20, 70:30, 65:35, and 60:40. We also provide tailored molecular weights, end-group modifications, and physical forms to meet diverse application requirements.

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FAQ

How does the intrinsic viscosity range of 0.45–0.55 dl/g affect the degradation behaviour of PLGA in drug delivery systems?

The specified intrinsic viscosity affects the polymer chain length, which impacts the degradation rate. This property supports controlled erosion, essential for achieving a reliable drug release profile. Contact us.

What analytical methods verify the carboxyl termination in this PLGA variant?

Techniques such as Fourier-transform infrared spectroscopy and titrimetric analysis are employed to confirm the carboxyl groups, ensuring the functional termination meets design specifications. Contact us.

How does the variation in molecular weight between 53 and 70 kDa influence the mechanical properties of this PLGA?

The molecular weight range directly affects tensile strength and flexibility, striking a balance between processability and structural integrity, which is vital for applications requiring predictable performance. Contact us.

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