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BP11146 PLGA 65:35, Hydroxyl Terminated, IV: 0.65–0.8 dl/g, Mw: 88–117 kDa

Catalogue Number BP11146
Composition Poly(D, L-lactide-co-glycolide) 65:35, Hydroxyl Terminated
Form Powder

PLGA 65:35, Hydroxyl Terminated, IV: 0.65–0.8 dl/g, Mw: 88–117 kDa is a biodegradable copolymer formulated for applications requiring controlled degradation profiles. Manufactured by Stanford Advanced Materials (SAM), this polymer undergoes detailed melt flow and molecular weight distribution analysis during quality control, ensuring precise measurement of its intrinsic viscosity and molecular weight parameters. SAM employs systematic batch testing to monitor consistency and purity throughout production.

In addition to the standard 65:35 grade, SAM offers customised synthesis of PLGA copolymers with various lactide-to-glycolide ratios, such as 90:10, 85:15, 80:20, 70:30, 65:35, and 60:40. We also provide tailored molecular weights, end-group modifications, and physical forms to meet diverse application requirements.

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FAQ

How does the intrinsic viscosity range impact the polymer’s degradation rate?

The intrinsic viscosity range of 0.65 to 0.8 dl/g directly correlates with polymer chain length, affecting the degradation rate. A higher IV typically indicates longer chains and a slower degradation process, which is crucial in applications requiring prolonged material integrity.

What advantages does a hydroxyl termination provide in this copolymer?

Hydroxyl termination enhances the polymer’s compatibility with other chemical functionalities. It facilitates chain coupling reactions or further modifications, making the material adaptable for applications such as drug delivery systems and tissue engineering scaffolds.

How is the molecular weight range verified during production?

The molecular weight range, specified between 88 and 117 kDa, is verified through gel permeation chromatography. This technique ensures batch-to-batch consistency by providing accurate molecular weight distribution data. For additional queries, contact us.

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