BP11147 PLGA 65:35, Hydroxyl Terminated, IV: 0.8–1.0 dl/g, Mw: 117–158 kDa

PLGA 65:35, Hydroxyl Terminated, IV: 0.8–1.0 dl/g, Mw: 117–158 kDa Description

PLGA (poly(lactic-co-glycolic acid)) 65:35, Hydroxyl Terminated, with an intrinsic viscosity of 0.8–1.0 dl/g and a molecular weight range of 117–158 kDa, is synthesised via controlled copolymerisation. Its hydroxyl termination enhances functionalisation potential, while the intrinsic viscosity correlates with chain length, affecting degradation rates. These technical features are essential for applications requiring precise, predictable polymer resorption in biomedical research.

PLGA 65:35, Hydroxyl Terminated, IV: 0.8–1.0 dl/g, Mw: 117–158 kDa Applications

1.         Healthcare Applications
- Used as a biodegradable matrix in drug delivery systems to achieve sustained release by leveraging predictable degradation properties.
- Applied as scaffolding in tissue engineering constructs to support cell proliferation by utilising controlled resorption.

2.         Research Applications
- Employed in in vitro studies to model polymer degradation kinetics, providing a standard for comparative analysis in biomedical research.

PLGA 65:35, Hydroxyl Terminated, IV: 0.8–1.0 dl/g, Mw: 117–158 kDa Packing

The product is packaged in moisture-resistant, sealed containers to prevent contamination and ensure stability. Protective inner layers and desiccant inserts are used to maintain low humidity. The packaging is designed for secure transport and storage, with options for vacuum-sealed pouches available upon request to meet customised protection requirements.

Additional Information

Understanding the properties of PLGA is essential in biomedical research and development. The polymer's lactic-to-glycolic acid ratio plays a key role in determining its degradation kinetics, influencing its suitability for various drug delivery systems and tissue engineering applications. Research into copolymer behaviour underlies its application in developing matrices for controlled therapeutic release.

Advances in polymer synthesis techniques have allowed for the customisation of molecular weight and intrinsic viscosity, providing a platform for tailored material properties. This makes PLGA a fundamental material in studies addressing biocompatibility and controlled resorption, which are critical for developing subsequent in vitro models and regenerative medicine constructs.

Regulatory Note: This material is intended for industrial and research applications. It is the customer's responsibility to ensure compliance with all relevant safety and regulatory standards in their intended use.