PI11331 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS No.: 122111-11-9)

2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS No.: 122111-11-9) Description

The compound, with the formula C20H18F2O8S, incorporates a fluorinated carbohydrate framework with benzoate protective groups and a methanesulfonate moiety. Its molecular configuration is tailored for applications where controlled reactivity and steric hindrance are essential. The structured synthesis and consistent particle size allow users to achieve predictable outcomes in multistep organic syntheses by minimising side reactions.

2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS No.: 122111-11-9) Applications

1.         Pharmaceutical Manufacturing
   - Used as an intermediate in drug synthesis to achieve enhanced selectivity by leveraging sterically hindered fluorine substitutions.
   - Employed in the preparation of prodrug candidates to control reaction pathways through its protective benzoate groups.

2.         Chemical Research
   - Applied as a reagent in organic synthesis to study reaction mechanisms influenced by fluorinated substituents.
   - Used as a model compound in method development for selective transformation processes in medicinal chemistry.

2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS No.: 122111-11-9) Packing

The compound is packaged in sealed, moisture-resistant containers to prevent contamination and degradation. Protective inner liners and anti-static materials are applied to minimise physical damage during transit. Storage recommendations include a cool, dry environment away from direct light. Custom packaging options can be arranged to accommodate specific laboratory handling requirements.

Additional Information

Fluorinated carbohydrate derivatives are increasingly utilised in pharmaceutical synthesis, where subtle modifications in molecular structure can direct reaction outcomes. The presence of fluorine atoms is known to modulate both electronic and steric properties, which is critical in controlling reactivity profiles during complex chemical transformations.

The use of protective groups such as benzoates in these compounds ensures that sensitive functional groups remain intact throughout reaction sequences. Such intermediates play a significant role in organic synthesis, offering a balance between stability and reactivity that is essential for developing efficient synthetic routes.