PI11345 (R)-(-)-2-Chloromandelic acid (CAS No.: 52950-18-2)

Catalogue Number	PI11345
Purity	≥98%
CAS Number	52950-18-2
Form	Powder

(R)-(-)-2-Chloromandelic acid is a chiral intermediate used in pharmaceutical synthesis. Stanford Advanced Materials (SAM) manufactures this compound via a controlled process that emphasises batch consistency and impurity control. SAM employs analytical methods such as HPLC and NMR spectroscopy to verify product purity and enantiomeric excess, ensuring the compound meets strict specifications required for synthetic applications in pharmaceutical intermediates.

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FAQ

How can trace impurities in (R)-(-)-2-Chloromandelic acid affect its use in chiral synthesis?

Trace impurities may alter reaction stereochemistry, leading to inconsistent product outcomes. Laboratories must monitor impurity profiles using advanced chromatographic methods to detect and control such variations during synthetic reactions.

Which analytical technique is most effective for determining the enantiomeric excess of (R)-(-)-2-Chloromandelic acid?

High-performance liquid chromatography (HPLC) with a chiral stationary phase is effective for quantifying enantiomeric excess. This method provides detailed separation and accurate assessment of the compound’s chiral purity.

What storage conditions are recommended for maintaining the integrity of this pharmaceutical intermediate?

Store the compound in a cool, dry environment away from direct sunlight. Sealed, moisture-proof containers under inert conditions help minimise degradation and preserve its defined chemical properties.

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