CIT6884 Citric Acid Monohydrate Powder CAS No. 5949-29-1

Citrate Monohydrate Powder Description

Citrate Monohydrate Powder crystallises as translucent monoclinic prisms with a molecular weight of 210.14 g/mol and dehydration commencement at 40°C. Its triprotic carboxylic acid structure (pKa₁=3.1, pKa₂=4.8, pKa₃=6.4) offers high-affinity chelation to Ca²⁺- (log K=3.5) and Fe³⁺-ions (log K=11.5), thus enhancing functionality in ion sequencing systems. The compound exhibits solubility in water of 147 g/100mL at 25°C, ethanol solubility of 38 g/100mL, and negligible solubility in hydrocarbons. Thermal analysis indicates a crystalline water loss over the range of 40-75°C (endothermic peak at 52°C), followed by decomposition above 175°C. The specified qualities include controlled moisture (7.5-9.0%), sulfate ash (≤0.05%), oxalate (≤100 ppm), and heavy metal contamination (Lead ≤0.5 ppm) according to USP/EP monographs, ensuring batch consistency under GMP conditions. Hygroscopicity remains moderate under 65% relative humidity but increases significantly at higher humidity levels.

Citrate Monohydrate Powder Applications

Food and Beverages: Primary acidulant in liquid syrups and fruit preserves (E330); pH stabiliser for emulsions in dairy products.

Pharmaceutical Products: Key ingredient in effervescent granules (15-25% w/w); additive to anticoagulant citrate-dextrose solutions (ACD).

Industrial: Biodegradable chelator in cooling tower treatments (3-8% solutions); stabiliser for electroplating baths.

Agriculture: pH adjuster in hydroponic nutrient solutions; descaling agent for irrigation systems.

Cosmetics: Antioxidant synergist in creams; buffering agent for skincare formulations with pH 3-6.

Packaging of Citrate Monohydrate Powder

Our products are packaged in customised cartons of various sizes according to the dimensions of the material. Smaller items are securely packaged in PP cartons while larger items are placed in custom-built wooden crates. We ensure strict adherence to packaging customisation and the use of appropriate cushioning materials to guarantee optimal protection during transport.

Packaging: Carton, wooden crate, or custom.

Please review the packaging details for your information.

Manufacturing Process

1)Testing Procedures

(1) Chemical composition analysis - Verified with techniques such as GDMS or XRF to ensure compliance with purity requirements.

(2) Mechanical property testing - Includes tensile strength, yield strength, and elongation tests to assess material performance.

(3) Dimension measurement - Measures thickness, width, and length to ensure compliance with specified tolerances.

(4) Surface quality inspection - Checks for defects such as scratches, cracks, or inclusions through visual and ultrasonic inspection.

(5) Hardness testing - Determines material hardness to confirm uniformity and mechanical reliability.

For detailed information, please refer to the SAM Testing Procedures.

FAQs about Citrate Monohydrate Powder

Q1. What is the difference between monohydrate and anhydrous citrate?

Composition:

Monohydrate contains one water molecule (7.5-9.0% moisture content)

Anhydrous has ≤0.5% moisture content (CAS 77-92-9)

Usage:

Monohydrate: Preferred for liquid formulations (e.g., syrup, beverages) due to better solubility control

Anhydrous: Ideal for moisture-sensitive products (e.g., powdered mixtures)

Q2. Is it safe for food and beverages?

Safety Notes:

Excessive intake may lead to calcium deficiency (e.g., muscle cramps); children/adults should compensate with calcium-rich foods.

Not to be used in infant formula or pure milk (causes coagulation).

Q3. How should it be stored?

Conditions:

Temperature: 15-30°C.

Humidity: ≤65% RH (hygroscopic; clumps above 70% RH).

Shelf life:

3 years in sealed, light-proof containers.

Related Information

1.Common Preparation Methods

Commercial citrate monohydrate powder is produced via submerged fermentation of glucose syrup or beet molasses using Aspergillus niger strains under oxygen-limited conditions (30-32°C, pH 5.0-5.5). The fermented broth undergoes vacuum filtration to remove mycelia, subsequently precipitating calcium citrate tetrahydrate through controlled lime addition. Raw citric acid is released upon treatment with sulfuric acid, purified through activated carbon decolourisation and cation exchange chromatography. Crystallisation occurs in vacuum evaporators at 25-30°C with slow cooling, yielding monohydrate crystals containing structured water. Centrifugation separates the crystals from the mother liquor, and fluidised bed drying at 35-40°C and 40% relative humidity maintains hydration stability. Final milling achieves the desired particle size (80-500 μm) with <5% fines.